Clinical Trials AFR

The Atrial Flow Regulator is being evaluated for heart failure patients in two ongoing clinical studies (PRELIEVE and PROLONGER) and a prospective registry (AFteR), and in an ongoing clinical study for pulmonary arterial hypertension patients (PROPHET). Additional clinical studies are also being planned.

Heart Failure

Study

PRELIEVE Study

Currently enrolling patients in a multicenter Pilot Study to Assess Safety and Efficacy of a Novel Atrial Flow Regulator (AFR) in Heart Failure Patients

Study

PROLONGER Study

Currently enrolling patients in a multicenter study to assess invasive and non-invasive parameters that may predict clinical improvement in patients with congestive heart failure after implantation of the Atrial flow regulator (AFR) device 

Study

AFteR Registry

Currently enrolling patients in a multicenter registry to monitor the safety and effectiveness of the Atrial Flow Regulator (AFR) device in patients with heart failure

Pulmonary Arterial Hypertension

Study

PROPHET Study

Currently enrolling patients in a multicenter Pilot Study to Assess Safety and Efficacy of a Novel Atrial Flow Regulator (AFR) in Patients with Pulmonary Hypertension