Clinical Trials AFR

The Atrial Flow Regulator is being evaluated for heart failure patients in two ongoing clinical studies (PRELIEVE and PROLONGER) and a prospective registry (AFteR), and in an ongoing clinical study for pulmonary arterial hypertension patients (PROPHET). Additional clinical studies are also being planned.

Heart Failure

PRELIEVE Study
Currently enrolling patients in a multicenter Pilot Study to Assess Safety and Efficacy of a Novel Atrial Flow Regulator (AFR) in Heart Failure Patients

PROLONGER Study
Currently enrolling patients in a multicenter study to assess invasive and non-invasive parameters that may predict clinical improvement in patients with congestive heart failure after implantation of the Atrial flow regulator (AFR) device 

AFteR Registry
Currently enrolling patients in a multicenter registry to monitor the safety and effectiveness of the Atrial Flow Regulator (AFR) device in patients with heart failure

Pulmonary Arterial Hypertension

PROPHET Study
Currently enrolling patients in a multicenter Pilot Study to Assess Safety and Efficacy of a Novel Atrial Flow Regulator (AFR) in Patients with Pulmonary Hypertension