Clinical Trials AFR

The Atrial Flow Regulator is being evaluated for heart failure patients in two ongoing clinical studies (PRELIEVE and PROLONGER) and a prospective registry (AFteR), and in an ongoing clinical study for pulmonary arterial hypertension patients (PROPHET). Additional clinical studies are also being planned.

Heart Failure

PRELIEVE Study

Currently enrolling patients in a multicenter Pilot Study to Assess Safety and Efficacy of a Novel Atrial Flow Regulator (AFR) in Heart Failure Patients
Read more

PROLONGER Study

Currently enrolling patients in a multicenter study to assess invasive and non-invasive parameters that may predict clinical improvement in patients with congestive heart failure after implantation of the Atrial flow regulator (AFR) device 
Read more

AFteR Registry

Currently enrolling patients in a multicenter registry to monitor the safety and effectiveness of the Atrial Flow Regulator (AFR) device in patients with heart failure
Read more

Pulmonary Arterial Hypertension

PROPHET Study

Currently enrolling patients in a multicenter Pilot Study to Assess Safety and Efficacy of a Novel Atrial Flow Regulator (AFR) in Patients with Pulmonary Hypertension 
Read more